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.Management Sciences
Category: General Pharmacology
Drug efficacy refers to_________________?
A. Range of disease in which the drug beneficial
B. Maximal intensity of response that can be produced by the drug
C. The therapeutic does range of the drug
D. The therapeutic index of the drug
Idiosyncracy is known as to have_____________?
A. Genetic component
B. Psychological component
C. Psysiological component
D. Nutritional component
Complete drug elimination occurs after how many hours, if t½ is 4 hrs______________?
A. 12 hrs
B. 20 hrs
C. 25 hrs
D. 30 hrs
Drugs exhibiting first pass metabolism are all EXCEPT one______________?
A. Morphine
B. Nitroglycerine
C. Propranolol
D. Salicylates
Drugs showing zero order kinetics of elimination_____________?
A. Are more common than first order kinetics
B. Decrease in concentration exponentially with time
C. Have a half – life independent of dose
D. Show a plot of drug concentration versus time that is linear
Intramuscular route is precluded during the medication of________________?
A. Anti-hypertensives
B. Anti-diabetics
C. Anticoagulants
D. Anti-fibrinolytics
When allergic manifestations occur pursuant to use of antimicrobial agents, what of the following is seen____________?
A. Skin eruptions
B. Angioneurotic edema
C. Sialorrhea
D. Serum imbalance
E. Both A & B
The dose of a drug required to produce a specified effect in 50% of the population is_____________?
A. Ld50
B. Td50
C. Md50
D. Ed50
Drug binds to activate the receptor is same fashion, which directly or indirectly brings effect, is_____________?
A. Inverse agonist
B. Antagonist
C. Agonist
D. Partial agonist
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