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.Management Sciences
Category: General Pharmacology
All of the following statements regarding biovailability of a drug are true except______________?
A. It is the proportion (fraction) of unchanged drug that reaches the systemic circulation
B. Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration
C. Low oral biovailability always and necessarily mean poor absorption
D. Biovailability can be determined from plasma concentration or urinary excretion data
Immune mediated qualitative drug intolerance is called______________?
A. Super sensitivity
B. Idiosyncrasy
C. Hyper sensitivity
D. Hyper acidity
Loading dose depends on_____________?
A. Volume of distribution
B. Clearance
C. Rate of administration
D. Half life
IF patient suffered from exaggerated effect of pharmacological effect____________?
A. Idosyncrasy
B. Toxicity
C. Side effect
D. None of the above
Therapetic index indicates____________?
A. Drug toxicty
B. Drug potency
C. Drug safety
D. Drug’s Lethal effect
Neuro adaptation to drug is same as______________?
A. Physical dependence
B. Psychological dependence
C. Addiction
D. Habituation
Combination of ampicillin and gentamicin is an example of_____________?
A. Indifference
B. Synergy
C. Antagonism
D. Bacterial symbiosis
The phase I reactions of drug metabolism include The following except_____________?
A. Hydolysis
B. Reduction
C. Oxidation
D. Conjugation
Hepatic first pass metabolism is important in____________?
A. Drugs given IM
B. Drugs taken orally
C. Drugs given IV
D. None of the above
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