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.Management Sciences
Category: Chemotherapy
Metronidazole is a type of___________?
A. Broad spectrum antibiotic
B. Quinolone
C. Imidazole derivative
D. Antidepressant
Which among the following anti-HIV drugs in an inhibitor of viral fusion ?
A. Enfuvirtide
B. Nelfinavir
C. Efavirenz
D. Etanercept:
Drug chemically related to penicillins is_____________?
A. Tetracycline
B. Sulphonamide
C. Cephalosporin
D. Lincemycin
The mechanism of action of chloramphenicol is inhibition of synthesis of_____________?
A. Cell wall
B. Cell membrane
C. Protein
D. DNA
Mechanism of action of quinolones is______________?
A. Inhibits DNA gyrase
B. Inhibits Bacterial protein synthesis
C. Inhibits bacterial cell wall synthesis
D. Inhibits intake of folic acid
Antibiotic that interferes with DNA function is_____________?
A. Metronidazole
B. Nystatin
C. Tetracycline
D. Sulphonamides
While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of alteration in his appearance. His last CD4 count was 360 cells/mm. The doctor is offered post exposure prophylaxis. Which regimen should she take ?
A. Ziduvidine and Lamivudine
B. Ziduvidine and Lamivudine and Indivair
C. Ziduvidine and Lamivudine and Stavudine
D. Ziduvidine and Lamivudine and Abacavir
Not true about piperacilline is_______________?
A. Active against pseudomonas aeruginose
B. Inhibits Beta-lactamase
C. It is a ureido penicillin
D. Given parenterally
The bacterial resistance to tetracycline is due to___________?
A. Alteration of drug binding sites
B. Alteration of dehydrofolate reductase
C. Inactivation of drug by enzymes
D. Decreased uptake of drug by bacteria
AIDS is a disease if the immune system primarily affecting_____________?
A. Granulocytes
B. Immunoglobulins
C. Opsonins
D. T lymphocytes
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